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The trial ran for a little over a year and showed an average decrease in BMI of 16% (compared to 0.6% for placebo)

and maintained at 37C with a 5% CO 2 atmosphere in all experiments

In contrast, Cu 2+ and ATA@Cu NPs alleviated corneal edema and halted further ulcer deterioration, especially the ATA@Cu NPs, which significantly shrank the opacity in the early stage of the keratitis and reduced the clinical score to 5.33 1.16