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Half-Life The differences between clearance and half-life are important in defining the underlying mechanisms for the effect of a disease state on drug disposition

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[20] It can also be injected intravenously for the purpose of treating cyanide poisoning, as the hydroxyl group is displaced by cyanide, creating a non-toxic cyanocobalamin that is excreted in urine

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53,54 This distinction is conceptually important because it shifts the emphasis from ROS diffusion to self-propagating redox state transitions

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