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Some people may start to see results within a few weeks, while for others it may take a few months

A pilot study of phentermine added to liraglutide (a related GLP-1 agonist) showed no meaningful additional weight loss

doi: 10.1038/s41591-025-04102-x 17

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Likelihood aside, its worth taking these reports seriouslythere have been deaths related to semaglutides exacerbation of pancreatitis symptoms

These typically include a BMI of 30 kg/m or higher (or 27+ with weight-related comorbidities like hypertension or sleep apnea), combined with documented prediabetes