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Trx overexpression prevented eNOS glutathionylation and uncoupling in vivo in coronary arteries of ischemia/reperfusion treated mice and protected against myocardial infarction
Furthermore, it could be shown that DPP4 inhibition is clearly associated with significantly increased -cell mass and function in several models of T2DM (134136)
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doi: 10.3390/ijms20040941 246 MotoriE.PuyalJ.ToniN.GhanemA.AngeloniC.MalagutiM.et al
In vivo, arctigenin (0.4 mg/mouse per day) reduced peanut sIgE and histamine levels and also blocked hypothermia in a PNA murine model [76]
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