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Brain Behav Immun 55:8292 Shan Y, Tan S, Lin Y, Liao S, Zhang B, Chen X, Wang J, Deng Z, Zeng Q, Zhang L, Wang Y, Hu XQ, Qiu W, Peng L, Lu ZQ (2019) The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke
These formulations are typically unlicensed in the UK and must be supplied as MHRA-regulated 'specials'
The good news is that in general a) the concurrent use of clozapine with these medicines enhances outcomes, and b) they do not seem to cause significant side effects issues
If solubility is difficult, a small amount of dilute acetic acid (e.g., 0.1%) is commonly used in peptide labs to aid dissolution
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