IGFBP-3, insulin-like growth factor-binding protein 3
In addition to physiological changes that occur with aging, and also social risk factors, the elderly population is at a risk for protein malnutrition and vitamin deficiency
Elevated cortisol from chronic stress can break down the skin barrier and slow cellular repair which can lead to an overall dullness or cause breakouts
In a phase 2 obesity trial, the highest dose led to participants losing an average of 24.2% of their body weight over 48 weeks (a secondary endpoint)
Evidence from murine models demonstrates that SCFA supplementation consistently improves liver health, supporting the therapeutic potential of SCFA-based interventions for human liver disease and warranting clinical investigation (167, 168)
The 11.2% discontinuation rate at the highest dose tells us that for roughly 1 in 9 patients, side effects were severe enough to stop treatment