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LIN28A can activate AR via c-mycregulation and promotes malignancy of ER-/Her2 + BC [63], thus providing strong evidence that curcumin can directly or indirectly interact with androgen signaling pathways and can affect tumor progression by regulating androgen signaling
The cell-line findings sit within a broader telomerase-mechanism literature compiled in 2013 and 2020 reviews
Angiogenesis Seiwerth et al
10.1126/science.7624778 29 CannonB.NedergaardJ
This approach ensures doses align with appetite shifts, nutrition supports muscle, and minor adverse effects are caught early, turning scattered effort into measurable, consistent action
They ignore muscle loss
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