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The women all lost substantial weight while on the drug
Tirzepatide targets two gut hormones: GIP GLP-1 Both influence appetite, insulin release, and energy balance, and both act on brain circuits that: Regulate reward Motivation Satiety GLP-1 receptor activity reaches areas of the brain involved in mood and cognition, and experimental work suggests GLP-1 agonists can reduce brain inflammation and support neurons
tirzepatide 15 mg, SURMOUNT-1, 72 weeks
Kruiswijk, F., Labuschagne, C
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Some research suggests that GLP-1 agonists may have anti-inflammatory effects that could theoretically influence the autoimmune process itself, though this remains speculative and has not been demonstrated in clinical trials specifically for thyroid autoimmunity
