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Discussion First-line treatment of CSU with H 1 -antihistamines often requires dose titration up to four times the standard dose, as recommended in guidelines [11]

Both of these processes are mainly regulated by the signaling pathway: insulin-like growth factor-1 (IGF-1) phosphoinositide-3-kinase (PI3K) protein kinase B (Akt) mammalian target of rapamycin (mTOR)

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SUMOylation refers to a post-translational modification in which small ubiquitin-like modifier (SUMO) proteins are attached to specific sites of a target protein, altering its conformation and activity without inducing degradation [103]

Artificial Elevation of Glutathione Levels in Tobacco In order to enhance glutathione contents in tobacco plants, we applied different methods

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