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A subcutaneous injection bypasses all gastrointestinal barriers entirely, delivering the intact molecule directly to the tissues where it can reach the bloodstream
It works by targeting receptors in the brain that control appetite and satiety, as well as receptors in the digestive tract that influence how quickly the stomach empties
Top Catal 69 , 533544 (2026)
In recent years, the therapeutic footprint of this class has grown: long-acting agents (e.g., liraglutide, semaglutide) and next-generation dual/triple agonists (e.g., tirzepatide) have demonstrated superior glycemic control, weight reduction, and cardiovascular benefits in adults with T2DM (Yao et al., 2024)
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