This man-made peptide comes from a protein in the stomach
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For diabetic retinopathy, the evidence was nuanced, indicating potential long-term neurovascular protection but also a risk of transient early worsening
For example, certain medications like Wegovy have shown cardiovascular benefits, which might make them a preferred choice for individuals with a higher risk of heart disease
The result is a mild natriuretic and diuretic effect
These opposing vectors may partially cancel out, which can be clinically useful in a patient who needs both an SNRI and a weight-loss agent but has borderline hypertension