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Zimmerman, M., Gottsater, A

Here we find increased proportion of pro-inflammatory and mesenchymal fibroblast subpopulations and senescent fibroblasts, and enhanced expression of senescence-associated secretory phenotype genes using single-cell RNA sequencing analysis, as well as elevated p16 protein and more -galactosidase-positive cells in keloids

Acute injuries often improved faster, while chronic degenerative conditions usually required longer timelines

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