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Nicotinamide adenine dinucleotide Nicotinamide adenine dinucleotide ( NAD ) is a coenzyme central to metabolism

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The elevated level of ATF3 in aging bone cells promotes iron absorption through the upregulation of TFR1, while concurrently suppressing cystine uptake facilitated by SLC7A11

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Additionally, oxidative stress can activate microglia and astrocytes, contributing to neuroinflammation and further neuronal damage [136, 149]