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Consider supplementation if sun exposure is limited, as vitamin D deficiency is common and may affect treatment outcomes

Using a L-5-methyltetrahydrofolate instead of folic acid, and ensuring we have optimal B12 in the form of methylcobalamin, and vitamin B6 in P-5-P form are key in helping with these pathways

doi:10.1073/pnas.91.4.1234

Add more layers of clothing, drink a warm beverage, or move around to generate heat