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5 Therapeutic strategies targeting shared metabolic pathways in sarcopenia and atherosclerosis The recognition of shared pathways necessitates a shift from single-disease management to integrated strategies targeting IR, chronic inflammation, lipid dysregulation, and hormonal shifts to disrupt the bidirectional vicious cycle (136) (As shown in Table 2 )
Lastly, increased de novo lipogenesis, i.e., hepatic FFA synthesis, seems to contribute to lipid deposition (20)
Inflammatory bowel disease a radical view
Protein determination of mucosal samples was performed using a commercial reagent (BioRad)
doi:10.1016/j.smrv.2020.101385
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