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The total phenolic content was expressed as milligrams of gallic acid equivalents (mg GAE/kg dry matter), calculated based on a standard curve generated from gallic acid solutions of known concentrations [42]

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

The scientific rationale for a nutritional approach Several studies have revealed in patients with vitiligo specific nutritional and biological characteristics that justify nutritional support: Major oxidative stress in melanocytes: justification for antioxidants (vitamin C, E, glutathione, selenium) More frequent deficiencies in vitamin D, vitamin B12, folate and zinc in several studies Melanin synthesis dependent on precursors (tyrosine, phenylalanine) and enzymatic cofactors (copper, zinc) Documented action of certain plants (Ginkgo biloba, Polypodium leucotomos) in randomized clinical trials What the nutritional approach does not do Let's be clear and honest: It does not cure vitiligo It does not replace medical treatments It does not work for all patients Results are not guaranteed What it can do Support the physiological mechanisms of repigmentation Address nutritional deficiencies commonly found Reduce oxidative stress documented in patients Enhance the efficacy of phototherapy according to several studies Fit into a holistic approach with healthy lifestyle habits and medical follow-up The nutritional approach is therefore positioned as a complementary tool , never central, but which can have its place in a comprehensive management plan

10.1016/bs.apcsb.2019.01.001 43 GlP.NovotnM.VasilenkoT.DeptaF.ullaI.TomoriZ

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Thanks to carnitine it is possible to reduce the tremendously annoying accumulated fats at a faster rate than would be achieved with exercise alone