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In 2025, a smaller number of PDPs will be benchmark plans that is, PDPs available for no monthly premium to Medicare Part D enrollees receiving the Low-Income Subsidy (LIS) than in any year since Part D started

Diarrhea is also dehydrating, so its important to refuel with fluids and electrolytes when experiencing this side effect

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GLP-1 RA Adherence Shows Drop-Off After 1 Year Sabrina McCrear Christina Mattina Key Takeaways Over half of semaglutide users in Denmark discontinued within a year, with significant drop-off rates at 3, 6, and 9 months

Other noteworthy phase 3 trial readouts in 2025 include: Novo Nordisks evoke/evoke+ , investigating oral semaglutide in patients with early Alzheimers disease, potentially expanding the utility of GLP-1s beyond cardiometabolic indications