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The infarct size was reduced by 43% and 56% with 1.5 and 3 mM LC, respectively, and by 48% and 65% with the same concentrations of ALC

GLP-1 receptor agonist lixisenatide protects against high free fatty acids-induced oxidative stress and inflammatory response

and distinctive levels of 3-nitrotyrosine that did not correlate with ammonia in the plasma of studied patients

In the early years of GLP-1 RA use it was suggested, an increased risk of pancreatitis and pancreatic tumors related to the use of these anti-diabetics.26 However, large clinical trials and other subsequent studies did not confirm this finding accordingly, the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) concluded that a causal relationship between these drugs and the development of pancreatitis or pancreatic cancer could not be established.2731 Our study has several limitations

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