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Its a triple-action medication that mimics the effects of three hormones: GLP-1, GIP, and glucagon
This synthetic compound was shown to increase muscle mass by 2.5 times in animal studies, though it has never been studied in humans
Egger M, Davey Smith G, Schneider M, Minder C
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229 Subsequently, evidence of the ileal-brake activity of GLP-1 was further provided using the GLP-1R antagonist exendin 9-39
By integrating these receptor activities, Retatrutide creates a synergistic effect that addresses interconnected metabolic challenges
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