Heres whats happening Reason No
The scientists found mixed results: While some studies showed the drugs offer neuroprotective benefits, other studies in the review raised the alarm that some medications in the drug class may increase depression and suicidal ideality
And if you know anything about addiction, you know thats where the real battle is fought
Subsequent studies from other groups have confirmed our original findings.65 Pleiotropic effects involving distinctive receptors, including VEGFR2 and growth hormone receptors, distinctive pathways, including VEGFR2-AKT-eNOS, ERK , FAK-paxillin, FoxO3a, p-AKT, p-mTOR and p-GSK-3, and distinctive loops, including stimulation of the egr-1 gene and its corepressor gene naB2, and counteraction of increases in pro-inflammatory and procachectic cytokines, likely minimize the inherent lack of full understanding of the mechanisms that may be involved
GLP-1 RA medications such as Semaglutide (Ozempic/Wegovy), Tirzepatide (Mounjaro), etc
The last 5 years have seen the emergence of efficacious peptide-based therapies for obesity treatment that target glucagon-like peptide-1 receptor (GLP-1R), either selectively or via co-activation with related receptors, such as the glucose-dependent insulinotropic polypeptide and/or glucagon receptors 1