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Zepbound delivers dramatically superior weight loss results: participants in clinical trials lost an average of 21% body weight (approximately 48 lbs at the highest dose) compared to Trulicitys modest 4-7% weight loss (7-10 lbs)
Use detailed charting in your DEXA report to spot true 4-week trends
Source: Arrone, et al New England J of Medicine May 11, 2025 Implications for employers: Employers looking to cover GLP-1 medications for weight loss should review formulary options to best balance cost and clinical outcomes
Exercising enforcement discretion: The FDA could issue new or revised guidance communicating that it does not intend to take regulatory action against pharmacies that compound using some or all of the peptides brought to the PCAC
The maintenance dose is not the same for everyonesome maintain at 10 mg, while others may find 15 mg appropriate if well-tolerated
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