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Baseline testing before starting is essential

Participants achieved significant reductions in waist circumference and improvements in blood pressure and blood sugar control

Buckley ST, Schele SG, Kirk RK, Knudsen LB

J Clin Endocrinol Metab 2025

In particular, people with adrenal insufficiency, clotting disorders, diabetes, heart disease, and thyrotoxicosis should speak with a health care provider before beginning this medication