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However, with direct injection, if you do not need the additional B12, it may result in high levels in your blood that can cause side effects including gastrointestinal issues, headache and dizziness, tiredness and weakness, or skin irritation until the excess is flushed out via your kidneys and urine

Dosing here comes from preclinical animal research (Neelakantan et al., 2018 onward) and community-reported protocols

Some researchers have explored their combined use in laboratory settings, though the majority of published literature examines each compound independently

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