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Additionally, vitamin B12 is necessary for the metabolism of cells throughout the body, including those involved in energy production and DNA synthesis

A bone marrow transplant or stem cell transplant may cure sickle cell anemia

Vasanthasree Nair MBBS Last updated on 13th Jan, 2026 Introduction Its common to hear conversations about low vitamin B12, but seeing a high vitamin B12 level in your blood test results can be unexpected

However, it's important to recognize that while a B12 deficiency may contribute to depression in some cases, it is not the sole cause

Additional tests may include full blood count (to check for macrocytic anaemia), methylmalonic acid and homocysteine levels (which rise in B12 deficiency), and tests for intrinsic factor antibodies if pernicious anaemia is suspected