The authors proposed the following model of Se uptake to the brain via SELENOP-LRP8: SELENOP present in blood and CSF is taken up by LRP8-positive cells of BBB and BCB, resynthesized in neighboring astrocytes, and subsequently released to supply LRP8-positive neurons within the brain with Se Figure 2
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The receptor groups include C-type lectin receptors (CLRs), such as the mannose receptor, CLEC7A, CLEC4n, Mincle, and DC-SIGN
Nanoparticle functionalization with platelet membrane enables multifactored biological targeting and detection of atherosclerosis