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Semaglutide is contraindicated in patients with a personal or family history of certain types of thyroid cancer, specifically thyroid C-cell tumors such as medullary thyroid carcinoma (MTC), or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)
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Collins, StatPearls , Glucagon-like Peptide-1 Receptor Agonists
UK pharmacy and clinical practice, guided by the Specialist Pharmacy Service (SPS), generally discourages the routine use of multi-dose vials and requires that any in-use shelf life and storage conditions follow validated, product-specific data
Taken together, the current clinical evidence suggests that tirzepatide is safe for long-term use in appropriate candidates, particularly under medical supervision with routine monitoring
