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Additionally, changes in insulin and insulin-like growth factor-1 (IGF-1) levels associated with improved glycemic control may have complex effects on bone remodeling

2 ~ 3:

When the body lacks adequate fluids, the digestive system may become irritated, leading to feelings of nausea and the urge to vomit

Thus, oral, but not i.p., administration of d-allulose suppressed food intake without inducing aversive behavior and influencing kidney functions

Initial effects include increased energy and improved mental clarity within the first week

For readers who want a broader foundation, this gut health microbiome guide explains how microbial balance, gut barrier resilience, inflammation, and digestive function work together