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A Review and Meta-Analysis of the Safety and Efficacy of Using Glucagon-like Peptide-1 Receptor Agonists

Seek immediate medical attention (A&E or call 999) if you develop: Severe, persistent vomiting preventing fluid intake for more than 24 hours Signs of severe dehydration: Confusion, extreme weakness, minimal urine output, or collapse Severe abdominal pain, particularly if accompanied by fever or vomiting Symptoms of pancreatitis: Severe upper abdominal pain radiating to the back, nausea, and vomiting (a rare but serious risk with GLP-1 receptor agonists) Patients should maintain open communication with their diabetes care team regarding any concerning symptoms

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Brightening is more gradual but delivers lasting results with continued use

Sources: Once-weekly semaglutide in adults with overweight or obesity

She is hardly alone: Of the estimated 48 million Americans with a substance use disorder, only 3 percent take a medication to address it