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If normally distributed, differences between the control and dietary intervention groups (cystine or BSO) were tested for significance using one-way ANOVA, followed by Bonferroni's multiple-comparison test

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Yes, enhanced monitoring is necessary including glucose parameters every 3 months, comprehensive metabolic panels every 36 months, periodic IGF-1 levels, and clinical surveillance for gastrointestinal symptoms, gallbladder disease, and growth hormone-related effects

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Vial-to-vial purity, sterility, and accuracy of stated mass vary by supplier