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Reducing Glucose Production : Semaglutide helps reduce the amount of glucose produced by the liver, which lowers overall blood sugar levels

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Patients should be encouraged to report all symptoms to their trial coordinator or supervising clinician, as this contributes to the broader evidence base needed for regulatory assessment

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Both short-acting and long-acting GLP-1 RAs have demonstrated beneficial effects by activating the AMPK-Sirt1 pathway, which has the potential to mitigate cardiac steatosis, oxidative stress, and apoptosis