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Their recommendations and resultant decision trees are summarized in Table 2 and Figure 2

Conversely, symptoms suggesting excessive thyroid hormone replacement (hyperthyroidism), including palpitations, tremor, anxiety, heat intolerance, or insomnia, particularly in the context of significant weight loss, warrant evaluation and possible levothyroxine dose reduction

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Essential Supplements for Bone Protection A targeted supplement regimen can make a significant difference in maintaining bone density: Calcium + Vitamin D3 Daily requirement : 1,000-1,200mg calcium and 2,000-5,000 IU vitamin D3 Best forms : Calcium citrate (more easily absorbed than calcium carbonate), vitamin D3 (cholecalciferol) Timing : Split calcium doses throughout the day for better absorption Vitamin K2 Daily requirement : 100- 200 mcg Function : Directs calcium to your bones rather than soft tissues and blood vessels Forms : MK-7 form has better bioavailability than MK-4 Magnesium Daily requirement : 320-420mg daily Forms : Magnesium glycinate or malate for better absorption and less digestive discomfort Benefits : Works synergistically with calcium and vitamin D Collagen Peptides Daily requirement : 10-15g Function : Provides the protein matrix upon which bone mineralization occurs Bonus : Also supports skin, hair, and joint health 2

Chambrier C, Laville M, Rhzioual Berrada K, Odeon M, Boultreau P, Beylot M

If you experience these symptoms, discuss a dose reduction with your provider rather than simply pushing through