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J Clin Invest (1984) 73:78593

Human pharmacokinetics, doseresponse, and mechanism validation remain limited

Conclusions These findings identify disrupted GSH homeostasis and inflammatory activation as metabolic features associated with symptomatic TTR-V30M amyloidosis in vivo, supporting a link between redox imbalance and disease manifestation

Roy M, Edde M, Fortier M, Croteau E, Castellano C-A, St-Pierre V, et al

Diabetes Technol Ther 26:184189 Shah VN, Akturk HK, Kruger D et al (2025) Semaglutide in adults with type 1 diabetes and obesity