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Pharmacokinetic drug interaction profiles of proton pump inhibitors: an update

Kothare PA, Soon DKW, Linnebjerg H, Park S, Chan C, Yeo A, et al

The headaches most commonly reported in semaglutide trials are described as mild, non-pulsating, and lacking the nausea, light sensitivity, and functional impairment that characterize true migraine attacks

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Not a restart, but you will start Wegovy at a lower dose than you were taking with Mounjaro