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Wilmot EG, Edwardson CL, Achana FA, Davies MJ, Gorely T, Gray LJ, et al
ACS Pharmacol Transl Sci
This personalised approach ensures that patients maximise the benefits of GLP-1 therapy while minimising adverse effects
PROMOTES DETOXIFICATION: Glutathione conjugation (facilitated by glutathione transferase enzymes) helps contribute to detoxification by binding electrophiles that would otherwise bind to proteins or nucleic acids, resulting in cellular damage
Given that these medications slow the speed at which stomach contents are moved farther down the gastrointestinal tract, bothersome side effects can be reduced by consuming smaller, though perhaps more frequent, meals
Analysis of clinical chemistry parameters measured at the end of the 4-week study (Supplementary Table 11) showed that MEDI4166 treatment reduced FPG, total cholesterol and serum alanine transaminase (ALT) levels, which is indicative of improved liver function
