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Scientific Activity In receptor assays, cagrilintide activates calcitonin-family amylin receptors and the calcitonin receptor, coupling primarily to Gs and cyclic AMP signaling
Our structures of Cagri-AMYR-G s complexes allow direct examination of the influence of a C-terminal proline in an amylin-template peptide through comparison of the interactions formed by P37 Cagri to that of Y37 rAmy with the CTR and AMYRs
How is Melatonin Produced
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10.1111/j.1398-9995.2009.02301.x 60
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