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Monotherapy with duloxetine, pregabalin or amitriptyline is the standard first-line approach for painful DPN, each demonstrating 3050% reduction in pain scores in randomized trials and meta-analyses
In one of the most successful trials, participants had an average initial body weight of 231 pounds and a BMI of 38
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Which raises an obvious point: if a medication is changing your blood pressure, your glucose, your lipids, and your kidney markers, the person prescribing it should be the same person managing your blood pressure, glucose, lipids, and kidney function