Can You Be B12 Deficient
Current investigations explore relationships between NNMT inhibition and: Obesity research Healthy aging Cellular metabolism Mitochondrial biology Energy homeostasis Fat metabolism Glucose regulation Nutrient utilization Researchers also investigate whether NNMT inhibition influences broader biological pathways connected with longevity research and metabolic resilience
One key group includes individuals with pernicious anemia, an autoimmune condition that affects the bodys ability to absorb vitamin B12 from food
In a 23-week randomized clinical trial in humans, individuals taking AOD-9604 at 1 mg daily had an average of 2.8 kg weight reduction compared to a 0.8 kg weight reduction in those taking a placebo
Lancet 390 (10113), 26272642
However, very high doses may cause side effects such as: B12 can also interact with certain medications, including those used to treat acid reflux, such as Prilosec (omeprazole) and Prevacid (lansoprazole), as well as some diabetes medications, such as metformin