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Cancer 17 (1), 66
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Research Applications & Usage Information Redox Homeostasis and Oxidative Stress Models : Studies how shifts in GSH/GSSG affect ROS handling, stress signaling, and oxidative damage markers
Protocol design
For instance, for inflammatory pathways, blocking the expression of G6PD impaired pro-inflammatory cytokine expression and lipid accumulation in LPS-activated DCs ( de novo lipid synthesis, the loss of G6PD function also led to impaired NOS2 activity in Ms activated by LPS (61) or by IFN- and infected by Trypanosoma cruzi (62)
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