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Reactive oxygen species: role in the development of cancer and various chronic conditions

Antioxidant therapy in renal diseases Carotenoids, flavonoids, alkaloids, and other natural products have been shown to be effective as preventive and therapeutic agents against oxidative mechanisms occurring in kidney diseases (Kanlaya and Thongboonkerd 2019)

Luengo, A., Sullivan, L

MMP modulation Simply building more collagen doesn't help if degradation continues unchecked

however, with a very low degree of certainty, colchicine did not appear to reduce heart attack or stroke risk, but did appear to cause more diarrhea, when used in primary prevention