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Severe depletion in liver glutathione during physical exercise

Thiamine triphosphate is a non-coenzyme derivative of thiamine, probably involved in acetylcholine neurotransmission (141143)

Directly and indirectly through multiple reactions which include enzymatic reactions, glutathione is oxidized to form GSSG, which is then reduced to GSH, its "active form" by yet another enzymatic reaction (3)