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"Overall, our data perpetuate the safety concerns surrounding the incretin-based therapies, but maybe the most interesting finding is that, reassuringly, while tirzepatide displays an unprecedented glucose- and weight-lowering efficacy, it comes with a similar or even improved safety profile vs GLP-1 receptor agonists," said first author Irene Caruso, MD, PhD, of the Department of Precision and Regenerative Medicine and Ionian Area, Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy, while presenting the research at the European Association for the Study of Diabetes (EASD) 2024 Annual Meeting

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