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Healthy adults with adequate nutrition rarely develop a clinical deficiency
(PubMed) Kumaran S, Panneerselvam KS, Shila S, Sivarajan K, Panneerselvam C
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doi: 10.1097/00003246-200106000-00021 19
Side Effects Compared Both share similar GI side effect profiles since they both activate GLP-1 receptors: Tirzepatide generally shows lower GI side effect rates in trials, possibly because GIP receptor activation provides a "smoother" signaling profile than pure GLP-1 agonism
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