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On the contrary, GLP-1 suppresses glucagon secretion in both healthy individuals and those with T2DM under normoglycemia and hyperglycemia (58) but not during hypoglycemia (131), thereby reducing the potential for developing severe hyperglycemia or hypoglycemia

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Multiple mechanisms : the combination of improved glucose/insulin signaling + reduced inflammation + mitochondrial support + potential direct effects on amyloid/tau

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