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Its important to recognize that abruptly stopping GLP-1 therapy can lead to common challenges, including weight regain and anxiety about ending treatment

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Efficacy and safety of tirzepatide in patients with type 2 diabetes (SURPASS-1)

J Sports Med Phys Fitness 1998;38:281-5

Rats treated with 0.5mg/kg/day intraperitoneal MOTs-C for 12 weeks were noted to have improved mechanical efficiency of the myocardium during exercise training over the placebo group.7 Data on the impact of exogenous MOTs-C on exercise tolerance in humans is not available, though, studies of endogenous MOTs-C levels have noted an 11.9 fold increase in MOTs-C levels in skeletal muscle in response to exercise, as well as increases in circulating levels of MOTs-C by 1.5 fold during exercise.5 MOTs-C is also of interest for a potential impact on longevity

Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa