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The induction of osteoblastic ferroptosis by Ti nanoparticles and the subsequent reduction in osteogenic function observed in clinical PPO samples, an osteolysis mouse model, and during osteoblast differentiation were all correlated with a significant decrease in GPX4 expression

Epub 1997/01/01

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14 Additionally, another study found that patients who took 300 mg/day of oral GSH for 4 months showed reduced liver fat and damage markers, indicating potential benefits for NAFLD patients

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ROS are primarily generated as byproducts of mitochondrial respiration [2]