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Pharmacotherapy Obesity pharmacotherapy has recently experienced a revolution with the advent of glucagon-like-peptide (GLP)-1 agonists (for example, semaglutide), and subsequently multi-incretin receptor agonists including dual agonists (for example, gastric inhibitory polypeptide (GIP) analogue and a GLP-1 receptor agonist, Tirzepatide) and triple agonists (for example, GLP-1, GIP, and glucagon receptor (GCGR), Retatrutide)

Fundamentals of Toxicology: Essential Concepts and Applications

In this study, researchers used an animal model of cancer to establish the potential role of the ecosystem of the digestive tract, called the gut microbiome, in determining whether chemotherapy will be effective

Gavornik, P

In the STEP 1 trial, adults without diabetes lost an average of 14.9% of body weight over 68 weeks, versus 2.4% with placebo