According to the MHRA, recognised reactions to injectable hydroxocobalamin include injection site reactions, rash, pruritus, and rarely, acneiform eruptions
[3] [2] Where there is neurological involvement, the loading phase uses alternate-day injections until there is no further improvement, and maintenance is 1 mg every two months
The method of injection, which can be either intramuscular (IM) or subcutaneous (SC), determines the appropriate needle gauge and length
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10.1038/375061a0 73 ColletJ.-F.MessensJ