Ye J et al
Preclinical studies have shown that GLP-1RAs influence essential signaling pathways, including the activation of farnesoid X receptor (FXR) and liver X receptor (LXR), which are crucial in lipid metabolism and inflammation (Errafii et al., 2022)
A systematic review published in the journal Drug and Alcohol Dependence provides a detailed analysis of the findings of available clinical trials that investigated the effect of glucagon-like peptide-1 (GLP-1) receptor agonists on substance use disorder
GLP-1s are naturally-occurring hormones in the human body released from the gut after eating, and according to Mayo Clinic, GLP-1 medications are used to boost the amount of insulin our bodies make to keep our blood sugar within a normal range, as well as provide the sensation of fullness after a meal to curb cravings
Patients should consult with a qualified healthcare provider to determine the most suitable treatment based on their specific needs and goals
Maintaining an adequate GSH redox status and 25-hydroxy-vitamin D levels will have the potential to reduce oxidative stress, enhance immunity and diminish the adverse clinical consequences of COVID-19 especially in African American communities having glucose-6-phosphate dehydrogenase deficiency, enzyme necessary to prevent GSH exhaustion and depletion (Jain and Parsanathan, 2020
