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In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may worsen kidney problems

Molecular mechanisms of anti-estrogen therapy resistance and novel targeted therapies

Bian: No

Both share the same core heptapeptide sequence, but Melanotan II has a cyclic structure via a lactam bond between Asp and Lys residues, while PT-141 is the open-chain form with a free N-terminal carboxylic acid group

2018;173:972988.e23

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