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Drugs That Distort eGFR: Medications That Falsify Your Kidney Function Test At a glance eGFR estimates how well your kidneys filter blood, reported in mL/min/1.73 m Normal eGFR is 90 mL/min/1.73 m or above for most adults The 2021 CKD-EPI equation removed the race coefficient and relies on serum creatinine (or cystatin C) Trimethoprim can drop eGFR by 15 to 30% without real kidney injury Cobicistat (in Stribild, Genvoya) raises creatinine 0.1 to 0.15 mg/dL within the first four weeks SGLT2 inhibitors cause an initial eGFR dip of 3 to 5 mL/min/1.73 m that is hemodynamic, not toxic Cimetidine inhibits tubular creatinine secretion and falsely lowers eGFR NSAIDs, ACE inhibitors, and ARBs can reduce true GFR through hemodynamic changes Cystatin C-based eGFR avoids most creatinine-related drug artifacts Metformin and GLP-1 agonists have renal dosing thresholds that a falsely low eGFR could trigger prematurely What eGFR Actually Measures Estimated glomerular filtration rate (eGFR) is a calculation, not a direct measurement

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Glutamate impairs neurons and induces neurodegeneration through the activation of NMDA receptors and glutamate receptors in postsynaptic neurons

While spirulina, dried nori, barley grass and most other seaweeds contain some B12 (dirt even contains some), consuming these foods hasnt been shown to provide enough B12 to vegans

men should report severe abdominal pain or persistent vomiting to their clinician promptly

Molecular aspects of medicine , 30 (1-2), 112